Anti-gamma-aminobutyric acid type A receptor subunit alpha 1 antibodies are used for the immunodetection of the protein encoded by the GABRA1 gene. In humans, the canonical protein has a reported length of 456 amino acid residues and a mass of 51.8 kDa. Its subcellular localization is in the cytoplasmic vesicles and cell membrane. A member of the Ligand-gated ion channel (TC 1.A.9) protein family, it is known to be involved with signal transduction pathways. Post-translational modifications have been described, including glycosylation. The gene encoding this protein is implicated in Epilepsy. Other names for this target antigen include ECA4, EIEE19, EJM, EJM5, gamma-aminobutyric acid receptor subunit alpha-1, and DEE19. Gene orthologs have been identified in the mouse, rat, bovine, frog, chimpanzee and chicken species.