Anti-mitochondrial translation release factor 1 like antibodies are used for the immunodetection of the protein encoded by the MTRF1L gene. In humans, the canonical protein has a reported length of 380 amino acid residues and a mass of 43.6 kDa. Its subcellular localization is in the mitochondria. Alternative splicing is reported to yield 4 different isoforms for this protein. It is reported to be expressed in skeletal muscle. It is a member of the Prokaryotic/mitochondrial release factor protein family. Other names for this target antigen include MRF1L, mtRF1a, peptide chain release factor 1-like, mitochondrial, mitochondrial release factor 1 like, mitochondrial translational release factor 1 like, and HMRF1L. Gene orthologs have been identified in the mouse, rat, bovine, frog, chimpanzee and chicken species.