Anti-methyltransferase like 25B antibodies are used for the immunodetection of the protein encoded by the METTL25B gene. In humans, the canonical protein has a reported length of 475 amino acid residues and a mass of 53 kDa. Its subcellular localization is in the membrane. Alternative splicing is reported to yield 2 different isoforms for this protein. It is a member of the METTL25 protein family. Other names for this target antigen include CGI-41, RRNAD1, methyltransferase-like protein 25B, protein RRNAD1, ribosomal RNA adenine dimethylase domain containing 1, and C1orf66. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.