Anti-cyclic nucleotide gated channel subunit alpha 1 antibodies are used for the immunodetection of the protein encoded by the CNGA1 gene. In humans, the canonical protein has a reported length of 686 amino acid residues and a mass of 79.1 kDa. Its subcellular localization is in the cell membrane. A member of the Cyclic nucleotide-gated cation channel (TC 1.A.1.5) protein family, it is a known subunit of the rod cyclic GMP-gated cation channel, which is involved in the final stage of the phototransduction pathway. Post-translational modifications have been described, including glycosylation. The gene encoding this protein is implicated in Retinitis pigmentosa. Other names for this target antigen include CNCG1, CNG-1, CNG1, RCNC1, RCNCa, RCNCalpha, RP49, and CNCG. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.