Anti-citramalyl-CoA lyase antibodies are used for the immunodetection of the protein encoded by the CLYBL gene. In humans, the canonical protein has a reported length of 340 amino acid residues and a mass of 37.4 kDa. Its subcellular localization is in the mitochondria. Alternative splicing is reported to yield 2 different isoforms for this protein. A member of the HpcH/HpaI aldolase protein family, it is known to be involved with metabolic processes. Other names for this target antigen include (3S)-malyl-CoA thioesterase, beta-methylmalate synthase, citrate lyase beta like, citrate lyase subunit beta-like protein, mitochondrial, malate synthase, and citramalyl-CoA lyase, mitochondrial. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.