Anti-H1.6 linker histone, cluster member antibodies are used for the immunodetection of the protein encoded by the H1-6 gene. In humans, the canonical protein has a reported length of 207 amino acid residues and a mass of 22 kDa. Its subcellular localization is in the nucleus and chromosomes. It is reported to have testis-specific expression. A member of the Histone H1/H5 protein family, it is known to be involved with cell differentiation and spermatogenesis. Post-translational modifications have been described, including phosphorylation. Other names for this target antigen include H1FT, H1t, HIST1H1T, dJ221C16.2, histone H1t, H1 histone family, member T (testis-specific), histone 1, H1t, and H1.6. Gene orthologs have been identified in the mouse, rat and chimpanzee species.