Anti-peroxiredoxin like 2B antibodies are used for the immunodetection of the protein encoded by the PRXL2B gene. In humans, the canonical protein has a reported length of 198 amino acid residues and a mass of 21.2 kDa. Its subcellular localization is in the cytoplasm. Alternative splicing is reported to yield 6 different isoforms for this protein. A member of the Peroxiredoxin-like PRXL2 protein family, it is known to catalyze the reduction of prostaglandin-ethanolamide H(2) (prostamide H(2)) to prostamide F(2alpha) with NADPH as proton donor. Other names for this target antigen include family with sequence similarity 213 member B, prostamide/PG F synthase, prostamide/PGF synthase, thioredoxin-type PGF synthase, and prostamide/prostaglandin F synthase. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish and chimpanzee species.