Anti-MET transcriptional regulator MACC1 antibodies are used for the immunodetection of the protein encoded by the MACC1 gene. In humans, the canonical protein has a reported length of 852 amino acid residues and a mass of 96.6 kDa. Its subcellular localization is in the nucleus and cytoplasm. It is found to be highly expressed in metastasizing tumors. It is known to act as a transcription activator for MET and as a key regulator of HGF-MET signaling. Other names for this target antigen include MACC1, MET transcriptional regulator, SH3 domain-containing protein 7a5, metastasis associated in colon cancer 1, putative binding protein 7a5, and metastasis-associated in colon cancer protein 1. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.