Anti-FERM domain containing kindlin 1 antibodies are used for the immunodetection of the protein encoded by the FERMT1 gene. In humans, the canonical protein has a reported length of 677 amino acid residues and a mass of 77.4 kDa. Its subcellular localization is in the cell membrane and cytoplasm. Alternative splicing is reported to yield 4 different isoforms for this protein. It is reported to be expressed in the brain, skeletal muscle, kidney, colon, adrenal gland, prostate, and placenta. A member of the Kindlin protein family, it is known to be involved in cell adhesion. The gene encoding this protein is implicated in Kindler syndrome. Other names for this target antigen include UNC112 related protein 1, fermitin family member 1, kindlerin, kindlin 1, kindlin syndrome protein, and fermitin family homolog 1. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.