Anti-MEFV innate immuity regulator, pyrin antibodies are protein reagents that detect specific antigens. The MEFV innate immuity regulator, pyrin antigen is another term for the human protein MEFV innate immunity regulator, pyrin, encoded by the MEFV gene. The protein is reported to be involved in regulation of innate immunity and the inflammatory response in response to IFNG/IFN-gamma. Canonically, it has an amino acid length of 781 residues and a mass of 86.4 kilodaltons. Its subcellular localization is in the nucleus, cytoplasmic vesicles, and cytoplasm and it is reported to be expressed in peripheral blood leukocytes, particularly in mature granulocytes and to a lesser extent in monocytes but not in lymphocytes. Other alias names for MEFV innate immuity regulator, pyrin include FMF, MEF, and PAAND.