Anti-ALG5 dolichyl-phosphate beta-glucosyltransferase antibodies are used for the immunodetection of the protein encoded by the ALG5 gene. In humans, the canonical protein has a reported length of 324 amino acid residues and a mass of 36.9 kDa. Its subcellular localization is in the ER. Alternative splicing is reported to yield 2 different isoforms for this protein. It is reported to be expressed in the pancreas, placenta, liver, heart, brain, kidney, skeletal muscle, and lung. A member of the Glycosyltransferase 2 protein family, it is known to be required for the assembly of lipid-linked oligosaccharides in kidney epithelial cells, and protein N-glycosylation. Post-translational modifications have been described, including glycosylation. The gene encoding this protein is implicated in Polycystic kidney disease. Other names for this target antigen include bA421P11.2, dolichyl-phosphate beta-glucosyltransferase, Alg5, S. cerevisiae, homolog of, and PKD7. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.