Anti-SH3GL interacting endocytic adaptor 1 antibodies are used for the immunodetection of the protein encoded by the SGIP1 gene. In humans, the canonical protein has a reported length of 828 amino acid residues and a mass of 89.1 kDa. Its subcellular localization is in the membrane. Alternative splicing is reported to yield 5 different isoforms for this protein. It is notably expressed in the brain. It is believed to function in clathrin-mediated endocytosis. Other names for this target antigen include SH3 domain GRB2 like endophilin interacting protein 1, endophilin-3-interacting protein, and SH3-containing GRB2-like protein 3-interacting protein 1. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.