Anti-gamma-aminobutyric acid type A receptor subunit gamma3 antibodies are used for the immunodetection of the protein encoded by the GABRG3 gene. In humans, the canonical protein has a reported length of 467 amino acid residues and a mass of 54.3 kDa. Its subcellular localization is in the cell membrane. Alternative splicing is reported to yield 2 different isoforms for this protein. A member of the Ligand-gated ion channel (TC 1.A.9) protein family, it is known to be involved with the response to xenobiotic compounds and signal transduction pathways. Post-translational modifications have been described, including palmitoylation and glycosylation. Other names for this target antigen include GABA(A) receptor subunit gamma-3, GABA(G) receptor, gamma 3, gamma-aminobutyric acid (GABA) A receptor, gamma 3, and gamma-aminobutyric acid receptor subunit gamma-3. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.