Anti-DAB adaptor protein 1 antibodies are used for the immunodetection of the protein encoded by the DAB1 gene. In humans, the canonical protein has a reported length of 588 amino acid residues and a mass of 63.8 kDa. Alternative splicing is reported to yield 6 different isoforms for this protein. It is reported to be mainly expressed in the brain. It is noted to be involved in astrocyte differentiation and neuronal development. Post-translational modifications have been described, including phosphorylation. The gene encoding this protein is implicated in Spinocerebellar ataxia. Other names for this target antigen include disabled homolog 1, DAB1, reelin adaptor protein, Dab reelin signal transducer 1, Dab, reelin signal transducer, homolog 1, spinocerebellar ataxia 37, and SCA37. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.