Anti-LAS1 like ribosome biogenesis factor antibodies are used for the immunodetection of the protein encoded by the LAS1L gene. In humans, the canonical protein has a reported length of 734 amino acid residues and a mass of 83.1 kDa. Its subcellular localization is in the nucleus and cytoplasm. Alternative splicing is reported to yield 4 different isoforms for this protein. A member of the LAS1 protein family, it is reported to be involved in biogenesis of the 60S ribosomal subunit. The gene encoding this protein is implicated in Intellectual developmental disorder. Other names for this target antigen include ribosomal biogenesis protein LAS1L and protein LAS1 homolog. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.