Anti-SPT6 homolog, histone chaperone and transcription elongation factor antibodies are used for the immunodetection of the protein encoded by the SUPT6H gene. In humans, the canonical protein has a reported length of 1726 amino acid residues and a mass of 199.1 kDa. Its subcellular localization is in the nucleus. Alternative splicing is reported to yield 3 different isoforms for this protein. It is ubiquitously expressed across many tissue types. A member of the SPT6 protein family, it is known to be involved with mRNA processing. Other names for this target antigen include SPT6H, emb-5, transcription elongation factor SPT6, histone chaperone suppressor of Ty6, suppressor of Ty 6 homolog, and SPT6. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.