Anti-CBFA2/RUNX1 partner transcriptional co-repressor 3 antibodies are used for the immunodetection of the protein encoded by the CBFA2T3 gene. In humans, the canonical protein has a reported length of 653 amino acid residues and a mass of 71.2 kDa. Its subcellular localization is in the nucleus. Alternative splicing is reported to yield 4 different isoforms for this protein. It is reported to be widely expressed with higher expression in the heart, pancreas, skeletal muscle, spleen, thymus and peripheral blood leukocytes. A member of the CBFA2T protein family, it is reported to be a transcriptional corepressor, which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes. Other names for this target antigen include MTG16, MTGR2, RUNX1T3, ZMYND4, protein CBFA2T3, CBFA2/RUNX1 translocation partner 3, MTG8-related gene 2, and ETO2. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.