Anti-H2B clustered histone 12 antibodies are used for the immunodetection of the protein encoded by the H2BC12 gene. In humans, the canonical protein has a reported length of 126 amino acid residues and a mass of 13.9 kDa. Its subcellular localization is in the nucleus and chromosomes. A member of the Histone H2B protein family, it is an important component of nucleosome. Post-translational modifications have been described, including glycosylation, ubiquitination and phosphorylation. Other names for this target antigen include H2B K, H2B histone family, member T, HIRA-interacting protein 1, histone 1, H2bk, histone cluster 1 H2B family member k, and histone H2B type 1-K. Gene orthologs have been identified in the mouse, rat and chimpanzee species.