Anti-SUV39H2 histone lysine methyltransferase antibodies are used for the immunodetection of the protein encoded by the SUV39H2 gene. In humans, the canonical protein has a reported length of 410 amino acid residues and a mass of 46.7 kDa. Its subcellular localization is in the nucleus. Alternative splicing is reported to yield 3 different isoforms for this protein. A member of the Histone-lysine methyltransferase protein family, it is a known histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. Post-translational modifications have been described, including ubiquitination. Other names for this target antigen include H3-K9-HMTase 2, histone H3-K9 methyltransferase 2, histone methyltransferase SUV39H2, lysine N-methyltransferase 1B, and histone-lysine N-methyltransferase SUV39H2. Gene orthologs have been identified in the mouse, rat, bovine, frog, chimpanzee and chicken species.