Anti-L3MBTL histone methyl-lysine binding protein 2 antibodies are used for the immunodetection of the protein encoded by the L3MBTL2 gene. In humans, the canonical protein has a reported length of 705 amino acid residues and a mass of 79.1 kDa. Its subcellular localization is in the nucleus. Alternative splicing is reported to yield 3 different isoforms for this protein. It is noted to be involved in chromatin organization and the regulation of transcription. Other names for this target antigen include H-l(3)mbt-like protein 2, L(3)mbt-like protein 2, L3MBTL2, polycomb repressive complex 1 subunit, l(3)mbt-like 2, and lethal(3)malignant brain tumor-like protein 2. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.