Anti-L3MBTL histone methyl-lysine binding protein 1 antibodies are used for the immunodetection of the protein encoded by the L3MBTL1 gene. In humans, the canonical protein has a reported length of 840 amino acid residues and a mass of 92.3 kDa. Its subcellular localization is in the nucleus. Alternative splicing is reported to yield 5 different isoforms for this protein. It is widely expressed across many tissue types. It is noted to be involved in chromatin organization and the regulation of transcription. Post-translational modifications have been described, including ubiquitination. Other names for this target antigen include L3MBTL, ZC2HC3, dJ138B7.3, lethal(3)malignant brain tumor-like protein 1, L3MBTL1, histone methyl-lysine binding protein, and H-L(3)MBT. Gene orthologs have been identified in the mouse, rat, bovine, frog, chimpanzee and chicken species.