Anti-methyltransferase 13, eEF1A lysine and N-terminal methyltransferase antibodies are used for the immunodetection of the protein encoded by the METTL13 gene. In humans, the canonical protein has a reported length of 699 amino acid residues and a mass of 78.8 kDa. Its subcellular localization is in the nucleus, mitochondria, and cytoplasm. Alternative splicing is reported to yield 5 different isoforms for this protein. A member of the Methyltransferase protein superfamily, it is reported to be a dual methyltransferase that catalyzes methylation of elongation factor 1-alpha (EEF1A1 and EEF1A2) at two different positions, and is therefore involved in the regulation of mRNA translation. Other names for this target antigen include CGI-01, DFNB26, DFNB26M, DFNM1, EEF1AKNMT, KIAA0859, feat, and 5630401D24Rik. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.