Anti-T-box transcription factor 2 antibodies are used for the immunodetection of the protein encoded by the TBX2 gene. In humans, the canonical protein has a reported length of 712 amino acid residues and a mass of 75.1 kDa. Its subcellular localization is in the nucleus. It is notably expressed in adult in the kidney, lung, and placenta. It is known to be a transcription factor which acts as a transcriptional repressor. The gene encoding this protein is implicated in Vertebral anomalies and variable endocrine and T-cell dysfunction. Other names for this target antigen include T-box transcription factor TBX2, T-box 2, T-box protein 2, and VETD. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.