Anti-methyltransferase 4, N6-adenosine antibodies are used for the immunodetection of the protein encoded by the METTL4 gene. In humans, the canonical protein has a reported length of 472 amino acid residues and a mass of 54 kDa. Its subcellular localization is in the nucleus, mitochondria, and cytoplasm. A member of the MT-A70-like protein family, it is reported to be a n(6)-adenine-specific methyltransferase that can methylate both RNAs and DNA. Other names for this target antigen include N(6)-adenine-specific DNA methyltransferase METTL4, methyltransferase like 4, methyltransferase-like protein 4, and N(6)-adenine-specific methyltransferase METTL4. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.