Anti-CHM Rab escort protein antibodies are used for the immunodetection of the protein encoded by the CHM gene. In humans, the canonical protein has a reported length of 653 amino acid residues and a mass of 73.5 kDa. Its subcellular localization is in the cytoplasm. Alternative splicing is reported to yield 2 different isoforms for this protein. A member of the Rab GDI protein family, it is reported to be a substrate-binding subunit of the Rab geranylgeranyltransferase (GGTase) complex. The gene encoding this protein is implicated in Choroideremia. Other names for this target antigen include GGTA, REP-1, TCD, rab proteins geranylgeranyltransferase component A 1, and DXS540. Gene orthologs have been identified in the mouse, rat, bovine, frog, chimpanzee and chicken species.