Anti-HPS6 biogenesis of lysosomal organelles complex 2 subunit 3 antibodies are used for the immunodetection of the protein encoded by the HPS6 gene. In humans, the canonical protein has a reported length of 775 amino acid residues and a mass of 83 kDa. Its subcellular localization is in the lysosomes and cytoplasm. It is ubiquitously expressed across many tissue types. It is believed to regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. The gene encoding this protein is implicated in Hermansky-Pudlak syndrome. Other names for this target antigen include Hermansky-Pudlak syndrome-6 protein (HPS6), ruby-eye protein homolog, and BLOC-2 complex member HPS6. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.