Anti-VPS28 subunit of ESCRT-I antibodies are used for the immunodetection of the protein encoded by the VPS28 gene. In humans, the canonical protein has a reported length of 221 amino acid residues and a mass of 25.4 kDa. Its subcellular localization is in the cell membrane. Alternative splicing is reported to yield 2 different isoforms for this protein. A member of the VPS28 protein family, it is a known component of the ESCRT-I complex, a regulator of vesicular trafficking process. Other names for this target antigen include ESCRT-I complex subunit VPS28, VPS28, ESCRT-I subunit, vacuolar protein sorting 28 homolog, vacuolar protein sorting 28-like protein, and vacuolar protein sorting-associated protein 28 homolog. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.