Anti-SUV39H1 histone lysine methyltransferase antibodies are used for the immunodetection of the protein encoded by the SUV39H1 gene. In humans, the canonical protein has a reported length of 412 amino acid residues and a mass of 47.9 kDa. Its subcellular localization is in the nucleus. Alternative splicing is reported to yield 2 different isoforms for this protein. A member of the Histone-lysine methyltransferase protein family, it is a known histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. Post-translational modifications have been described, including ubiquitination, acetylation and phosphorylation. Other names for this target antigen include KMT1A, MG44, SUV39H, histone-lysine N-methyltransferase SUV39H1, Su(var)3-9 homolog 1, and H3-K9-HMTase 1. Gene orthologs have been identified in the mouse, rat, bovine and chimpanzee species.