Anti-gamma-aminobutyric acid type A receptor subunit rho1 antibodies are used for the immunodetection of the protein encoded by the GABRR1 gene. In humans, the canonical protein has a reported length of 479 amino acid residues and a mass of 55.9 kDa. Its subcellular localization is in the cell membrane. Alternative splicing is reported to yield 3 different isoforms for this protein. It is reported to be highly expressed in the retina and in a lesser extent in the brain, lung and thymus. A member of the Ligand-gated ion channel (TC 1.A.9) protein family, it is known to be involved with chemical synaptic transmission and signal transduction pathways. Post-translational modifications have been described, including glycosylation. Other names for this target antigen include GABA(A) receptor subunit rho-1, GABA(A) receptor, rho 1, GABA(C) receptor, bA135P14.1 (gamma-aminobutyric acid (GABA) receptor, rho 1), and gamma-aminobutyric acid receptor subunit rho-1. Gene orthologs have been identified in the mouse, rat, bovine and chimpanzee species.