Anti-trafficking protein particle complex subunit 9 antibodies are used for the immunodetection of the protein encoded by the TRAPPC9 gene. In humans, the canonical protein has a reported length of 1148 amino acid residues and a mass of 128.5 kDa. Its subcellular localization is in the ER, Golgi, and cytoplasm. Alternative splicing is reported to yield 3 different isoforms for this protein. It is notably expressed at high levels in muscle and kidney and to a lower extent in the brain, heart and placenta. A member of the NIBP protein family, it is known to function as a activator of NF-kappa-B through increased phosphorylation of the IKK complex. The gene encoding this protein is implicated in Intellectual developmental disorder. Other names for this target antigen include NIK and IKK-beta binding protein, NIK- and IKBKB-binding protein, TRAPP 120 kDa subunit, trafficking protein particle complex 9, tularik gene 1 protein, and IKK2 binding protein. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.