Anti-H2A.Z variant histone 2 antibodies are used for the immunodetection of the protein encoded by the H2AZ2 gene. In humans, the canonical protein has a reported length of 128 amino acid residues and a mass of 13.5 kDa. Its subcellular localization is in the nucleus and chromosomes. Alternative splicing is reported to yield 5 different isoforms for this protein. It is a member of the Histone H2A protein family. Post-translational modifications have been described, including ubiquitination and acetylation. Other names for this target antigen include H2A histone family member V, H2A.F/Z, histone H2A.F/Z, purine-rich binding element protein B, and histone H2A.V. Gene orthologs have been identified in the mouse, rat, bovine, frog and chimpanzee species.