Anti-SRY-box transcription factor 11 antibodies are used for the immunodetection of the protein encoded by the SOX11 gene. In humans, the canonical protein has a reported length of 441 amino acid residues and a mass of 46.7 kDa. Its subcellular localization is in the nucleus. It is notably expressed in the brain and heart, with low expression in the kidney, pancreas and muscle. It is reported to be a transcription factor that acts as a transcriptional activator. The gene encoding this protein is implicated in Coffin-Siris syndrome. Other names for this target antigen include IDDMOH, MRD27, transcription factor SOX-11, SRY (sex-determining region Y)-box 11, SRY-box 11, and CSS9. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.