Anti-WARS1 antibodies are used in the immunodetection of the protein tryptophanyl-tRNA synthetase 1. In humans, the canonical protein has a reported length of 471 amino acid residues and a mass of 53.2 kDa. Its subcellular localization is in the cytoplasm. Up to 2 different isoforms have been reported for this protein. It is notably expressed in many tissues, such as the kidney and rectum. A member of the Class-I aminoacyl-tRNA synthetase protein family, WARS1 is known to be involved with angiogenesis and the regulation of cell proliferation. Post-translational modifications have been described, including protein cleavage. The WARS1 gene has been associated with the disease, Neuronopathy. Synonyms for this target antigen include HMN9, IFI53, IFP53, NEDMSBA, WARS, and GAMMA-2. WARS1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.