Anti-osteoclast associated Ig-like receptor antibodies are used for the immunodetection of the protein encoded by the OSCAR gene. In humans, the canonical protein has a reported length of 282 amino acid residues and a mass of 30.5 kDa. Its subcellular localization is in the cell membrane and is secreted. Alternative splicing is reported to yield 7 different isoforms for this protein. A member of the Leukocyte receptor complex/polymeric immunoglobulin receptor (PIR/LRC) protein family, it is a reported regulator of osteoclastogenesis which plays an important bone-specific function in osteoclast differentiation. Post-translational modifications have been described, including glycosylation. Other names for this target antigen include osteoclast associated receptor OSCAR-S1, osteoclast associated receptor OSCAR-S2, osteoclast associated, immunoglobulin-like receptor, and osteoclast-associated immunoglobulin-like receptor. Gene orthologs have been identified in the mouse, rat, bovine and chimpanzee species.