Anti-CLPTM1 regulator of GABA type A receptor forward trafficking antibodies are used for the immunodetection of the protein encoded by the CLPTM1 gene. In humans, the canonical protein has a reported length of 669 amino acid residues and a mass of 76.1 kDa. Its subcellular localization is in the membrane. Alternative splicing is reported to yield 3 different isoforms for this protein. It is widely expressed across many tissue types. A member of the CLPTM1 protein family, it is known to be involved in GABAergic but not glutamatergic transmission. Post-translational modifications have been described, including glycosylation. Other names for this target antigen include CLPTM1, transmembrane protein, cleft lip and palate associated transmembrane protein 1, cleft lip and palate transmembrane protein 1, and putative lipid scramblase CLPTM1. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish and chimpanzee species.