Anti-nucleoporin 42 antibodies are used for the immunodetection of the protein encoded by the NUP42 gene. In humans, the canonical protein has a reported length of 423 amino acid residues and a mass of 44.9 kDa. Its subcellular localization is in the nucleus and membrane. Alternative splicing is reported to yield 3 different isoforms for this protein. It is ubiquitously expressed across many tissue types. It is known to be required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. Post-translational modifications have been described, including O-glycosylation. Other names for this target antigen include NLP-1, NLP1, NLP_1, NUPL2, UIP1, hCG1, nucleoporin NUP42, and CG1. Gene orthologs have been identified in the mouse, rat, bovine, frog and chimpanzee species.