Anti-protein tyrosine phosphatase non-receptor type 18 antibodies are used for the immunodetection of the protein encoded by the PTPN18 gene. In humans, the canonical protein has a reported length of 460 amino acid residues and a mass of 50.5 kDa. Its subcellular localization is in the nucleus and cytoplasm. Alternative splicing is reported to yield 2 different isoforms for this protein. It is reported to be expressed in the brain, colon and several tumor-derived cell lines. A member of the Protein-tyrosine phosphatase protein family, it is known to be involved with protein dephosphorylation. Other names for this target antigen include PTP-HSCF, tyrosine-protein phosphatase non-receptor type 18, brain-derived phosphatase, protein tyrosine phosphatase, non-receptor type 18 (brain-derived), and BDP1. Gene orthologs have been identified in the mouse, rat, bovine, frog and chimpanzee species.