Anti-protein tyrosine phosphatase non-receptor type 14 antibodies are used for the immunodetection of the protein encoded by the PTPN14 gene. In humans, the canonical protein has a reported length of 1187 amino acid residues and a mass of 135.3 kDa. Its subcellular localization is in the nucleus and cytoplasm. It is ubiquitously expressed across many tissue types. A member of the Protein-tyrosine phosphatase protein family, it is known to be involved with the regulation of cell proliferation and protein dephosphorylation. Post-translational modifications have been described, including ubiquitination. The gene encoding this protein is implicated in Choanal atresia and lymphedema. Other names for this target antigen include PEZ, PTP36, PTPD2, tyrosine-protein phosphatase non-receptor type 14, cytoskeletal-associated protein tyrosine phosphatase, and CATLPH. Gene orthologs have been identified in the mouse, rat, bovine, frog, chimpanzee and chicken species.