Anti-TPX2 microtubule nucleation factor antibodies are used for the immunodetection of the protein encoded by the TPX2 gene. In humans, the canonical protein has a reported length of 747 amino acid residues and a mass of 85.7 kDa. Its subcellular localization is in the nucleus and cytoplasm. Alternative splicing is reported to yield 2 different isoforms for this protein. It is reported to be expressed in the lung carcinoma cell lines but not in normal lung tissues. A member of the TPX2 protein family, it is known to be involved with the apoptotic pathway and cell division. Other names for this target antigen include C20orf2, DIL-2, DIL2, FLS353, GD:C20orf1, HCA519, HCTP4, and C20orf1. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.