Anti-Anoctamin 5 antibodies are used in the immunodetection of the protein encoded by the ANO5 gene. In humans, the canonical protein has a reported length of 913 amino acid residues and a mass of 107.2 kDa. Its subcellular localization is in the ER and cell membrane. It is reported to be highly expressed in the brain, heart, kidney, lung, and skeletal muscle. The anoctamin 5 protein is a member of the Anoctamin protein family. Post-translational modifications have been described, including glycosylation. Other names for this target antigen include integral membrane protein GDD1, transmembrane protein 16E, and gnathodiaphyseal dysplasia 1 protein.