Anti-PEA15 antibodies are used in the immunodetection of the protein proliferation and apoptosis adaptor protein 15. In humans, the canonical protein has a reported length of 130 amino acid residues and a mass of 15 kDa. Its subcellular localization is in the cytoplasm. Up to 2 different isoforms have been reported for this protein. It is ubiquitously expressed across many tissue types. PEA15 is known to be involved with the apoptotic pathway and MAPK cascade signaling pathways. Post-translational modifications have been described, including phosphorylation. Synonyms for this target antigen include HUMMAT1H, MAT1, MAT1H, PED, PED-PEA15, PED/PEA15, astrocytic phosphoprotein PEA-15, and HMAT1. PEA15 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.