Anti-MED16 antibodies are used in the immunodetection of the protein mediator complex subunit 16. In humans, the canonical protein has a reported length of 877 amino acid residues and a mass of 96.8 kDa. Its subcellular localization is in the nucleus. Up to 5 different isoforms have been reported for this protein. A member of the Mediator complex subunit 16 protein family, med16 is a known component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Synonyms for this target antigen include THRAP5, TRAP95, mediator of RNA polymerase II transcription subunit 16, and DRIP92. MED16 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of med16 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.