Anti-Anoctamin 4 antibodies are used for the immunodetection of the protein encoded by the ANO4 gene. In humans, the canonical protein has a reported length of 955 amino acid residues and a mass of 111.5 kDa. Its subcellular localization is in the cell membrane. Alternative splicing is reported to yield 3 different isoforms for this protein. A member of the Anoctamin protein family, it is known to have calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Post-translational modifications have been described, including glycosylation. Other names for this target antigen include transmembrane protein 16D. Gene orthologs have been identified in the mouse, rat, bovine, frog, chimpanzee and chicken species. ELISA is a widely used application for the Anoctamin 4 antibodies listed below. In addition, Western Blot is also a common application.