Anti-Keratin 25 antibodies are used for the immunodetection of the protein encoded by the KRT25 gene. In humans, the canonical protein has a reported length of 450 amino acid residues and a mass of 49.3 kDa. Its subcellular localization is in the cytoplasm. It is reported to be highly expressed in skin and scalp, and weak expression observed in thymus and tongue. A member of the Intermediate filament protein family, it is known to be important for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). The gene encoding this protein is implicated in Woolly hair autosomal recessive. Other names for this target antigen include CK-25, K25, K25A, cytokeratin-25, keratin 25, type I, keratin-25A, and keratin, type I cytoskeletal 25. Gene orthologs have been identified in the mouse, rat, bovine and chimpanzee species. These Keratin 25 antibodies are widely used in Western Blot experiments, among other applications.