Anti-Claspin antibodies are used for the immunodetection of the protein encoded by the CLSPN gene. In humans, the canonical protein has a reported length of 1339 amino acid residues and a mass of 151.1 kDa. Its subcellular localization is in the nucleus. Alternative splicing is reported to yield 3 different isoforms for this protein. A member of the Claspin protein family, it is known to be required for checkpoint mediated cell cycle arrest in response to inhibition of DNA replication or to DNA damage induced by both ionizing and UV irradiation. Post-translational modifications have been described, including ubiquitination, protein cleavage and phosphorylation. Other names for this target antigen include claspin homolog. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 60 citations in the literature describe the use of Claspin antibodies in research. These antibodies are most commonly used in Western Blot experiments, among other applications.