Anti-PDE6H antibodies are used in the immunodetection of the protein phosphodiesterase 6H. In humans, the canonical protein has a reported length of 83 amino acid residues and a mass of 9.1 kDa. It is notably expressed in the retina. A member of the Rod/cone cGMP-PDE gamma subunit protein family, PDE6H is known to participate in processes of transmission and amplification of the visual signal. The PDE6H marker can be used to identify Retinal Cone Cells.* Synonyms for this target antigen include RCD3, retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma, GMP-PDE gamma, phosphodiesterase 6H, cGMP-specific, cone, gamma, and ACHM6. PDE6H gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Some PDE6H antibodies may have been used in research and have associated citations. ELISA is a widely used application for these antibodies. In addition, Western Blot is also a common application.
*HuBMAP Human Reference Atlas v1.4