Anti-NPPC antibodies are used in the immunodetection of the protein natriuretic peptide C. In humans, the canonical protein has a reported length of 126 amino acid residues and a mass of 13.2 kDa. It has been described to be a secreted protein. A member of the Natriuretic peptide protein family, NPPC is reported to be a type of hormone, which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation (By similarity). The NPPC marker can be used to identify Midbrain-Derived Inhibitory Neurons.* Synonyms for this target antigen include CNP2, C-type natriuretic peptide, natriuretic peptide precursor type C, and CNP. NPPC gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species.
*HuBMAP Human Reference Atlas v1.4