Anti-CDC42BPB antibodies are used in the immunodetection of the protein CDC42 binding protein kinase beta. In humans, the canonical protein has a reported length of 1711 amino acid residues and a mass of 194.3 kDa. Its subcellular localization is in the cell membrane and cytoplasm. It is reported to be expressed in all tissues examined, with high levels in the heart, brain, placenta and lung. A member of the AGC Ser/Thr protein kinase protein family, CDC42BPB is reported to be a serine/threonine-protein kinase, which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. Synonyms for this target antigen include MRCKB, serine/threonine-protein kinase MRCK beta, CDC42 binding protein kinase beta (DMPK-like), CDC42BP-beta, DMPK-like beta, and CHOCNS. CDC42BPB gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Western Blot is the most common application for the CDC42BPB antibodies listed below. ELISA and Immunohistochemistry are also common applications.