Anti-SNRPE antibodies are used in the immunodetection of the protein small nuclear ribonucleoprotein polypeptide E. In humans, the canonical protein has a reported length of 92 amino acid residues and a mass of 10.8 kDa. Its subcellular localization is in the nucleus and cytoplasm. It is widely expressed across many tissue types. A member of the SnRNP Sm proteins protein family, SNRPE is reported to play a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Synonyms for this target antigen include SME, Sm-E, snRNP-E, small nuclear ribonucleoprotein E, sm protein E, and HYPT11. SNRPE gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some SNRPE antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.