Anti-KIDINS220 antibodies are used in the immunodetection of the protein kinase D interacting substrate 220. In humans, the canonical protein has a reported length of 1771 amino acid residues and a mass of 196.5 kDa. Its subcellular localization is in the membrane. Up to 5 different isoforms have been reported for this protein. It is notably expressed in developing and adult neural tissues as well as neuroendocrine cells and dendritic cells. KIDINS220 is reported to promote a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Post-translational modifications have been described, including phosphorylation. Synonyms for this target antigen include ankyrin repeat-rich membrane-spanning protein, kinase D-interacting substrate 220kDa, and kinase D-interacting substrate of 220 kDa. KIDINS220 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some KIDINS220 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.